NCT03310047

Intra-individual Reproducibility in Nerve Block Duration

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Nordsjaellands Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

An interventional randomized controlled crossover trial, to illuminate if durations in nerve block durations are predictable within the same subject.

Detailed description

An interventional randomized controlled crossover trial, with the purpose to elucidate the reproducibility in nerve block duration on 20 healthy volunteers in Denmark. There will be two trial arms: 1: Day one; Right side low dose nerve block and left side high dose nerve block. Repeated after 24 hours. Day three; Left side low dose nerve block and right side high dose nerve block. Repeated after 24 hours 2: Day one; Left side low dose nerve block and right side high dose nerve block Repeated after 24 hours Day three; Right side low dose nerve block and left side high dose nerve block Repeated after 24 hours All volunteers will receive two peripheral nerve blocking catheters adjacent to the common peroneal nerve and will be treated two times on each side with Lidocaine 0.5% 5 mL and 10 mL.

Conditions

• Anesthesia, Regional

Interventions

Type	Name	Description
DRUG	Infusion, Lidocaine, 0.5%, 5 mL	A catheter-based perineural infusion of 5 mL Lidocaine 0.5%
DRUG	Infusion, Lidocaine, 0.5%, 10 mL	A catheter-based perineural infusion of 10 mL Lidocaine 0.5%

Timeline

• Start date: 2017-10-30
• Primary completion: 2018-03-01
• Completion: 2018-03-01
• First posted: 2017-10-16
• Last updated: 2018-05-15

Locations

1 site across 1 country: Denmark