NCT03307005

Improving Sleep Quality in Heart Failure

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 5 (actual)
• Sponsor: Johns Hopkins University · Academic / Other
• Sex: All
• Age: 21 Years – 79 Years
• Healthy volunteers: Not accepted

Summary

Poor sleep quality is common in patients with heart failure. The limited available evidence intimates that improving sleep quality in patients with heart failure may improve morbidity and quality of life in this patient population. However, there is a paucity of evidence assessing the use of effective pharmacologic therapies in heart failure. The nonbenzodiazepine, GABA receptor agonist, zolpidem, has been found to have considerable benefits over traditional benzodiazepines as a soporific medication. The investigators hypothesize that zolpidem will safely improve sleep quality in patients with heart failure.

Conditions

• Sleep Disturbance
• Heart Failure

Interventions

Type	Name	Description
DRUG	Zolpidem Tartrate	Zolpidem tartrate 5 mg capsule one per night taken for 7 nights
DRUG	Placebo oral capsule	Placebo capsule one per night taken for 7 nights

Timeline

• Start date: 2017-11-01
• Primary completion: 2019-01-25
• Completion: 2019-01-25
• First posted: 2017-10-11
• Last updated: 2020-02-11
• Results posted: 2020-02-11

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study