NCT03306134

The Effect of Beta-blockers in Substance P Levels and the Swallowing Function

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 60 (estimated)
• Sponsor: Hospital de Mataró · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

A non-randomised, prospective study to assess the effects of beta-blockers on substance P levels and the swallowing function. The study is going to be carry out in the Gastrointestinal Physiology Laboratory of the Hospital de Mataró (Spain). All participants will be actively recruited from a Linked hospital and primary care database. We include two groups: the first group (group 1) are participants taking beta-blockers and the second group (group 2) are participants not-taking beta-blockers.

Conditions

• Beta Blockers
• Swallowing Disorder
• Substance P

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Dysphagia	An overall assessment is going to be carry out by a multidisciplinary team during the visit. Swallowing assessment is going to be performed during the visit. We are going to use: (i) the Eating Assessment Tool (EAT-10), which is a short 10-item, easy to use, self-administered questionnaire \[4\]. Although the EAT-10 is considered to be predominantly a questionnaire on FHS, some items on HR-QoL are also included. The sum score of this 10-item questionnaire ranges from 0 to 40, and (ii) the Sydney Swallowing Questionnaire (SSQ) to clinically assess the severity of the symptoms of dysphagia, if present. All subjects are going to be submitted to the volume-viscosity swallow test (V- VST)

Timeline

• Start date: 2017-06-05
• Primary completion: 2018-11-25
• Completion: 2018-12-31
• First posted: 2017-10-10
• Last updated: 2018-02-22

Locations

1 site across 1 country: Spain