Trials / Completed
CompletedNCT03305900
Determinants of Formate Concentrations
Lifestyle, Metabolite and Genetic Determinants of Formate Concentrations in a Cross-sectional Study of Young, Healthy Adults
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 1,701 (actual)
- Sponsor
- Memorial University of Newfoundland · Academic / Other
- Sex
- All
- Age
- 18 Years – 28 Years
- Healthy volunteers
- Accepted
Summary
Formate is an important metabolite, serving as a donor of one-carbon groups to the intracellular tetrahydrofolate pool. However, little is known of its circulating concentrations or of their determinants. This study seeks to define formate levels and their determinants in a young, healthy population. Serum formate will be measured in 1701 subjects from the Trinity Student Study. The subjects, males and females, aged 18 to 28 years, were enrolled at Trinity College, Dublin. Formate levels will be compared with other one-carbon metabolites, vitamin status, potential formate precursors, genetic polymorphisms, and lifestyle factors.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | No Intervention | Cross-sectional study requiring a single serum sample |
Timeline
- Start date
- 2012-12-01
- Primary completion
- 2013-11-26
- Completion
- 2013-11-26
- First posted
- 2017-10-10
- Last updated
- 2017-10-10
Source: ClinicalTrials.gov record NCT03305900. Inclusion in this directory is not an endorsement.