NCT03305705

Effect of Iron on Cerebral Dopamine Receptor Density in Non-anaemic Premenopausal Women With Low Ferritin and Fatigue

Double-Blind, Single-Center Interventional Trial To Evaluate The Effect Of Intravenous Iron Versus Placebo On Cerebral Dopamine Receptor Density In Non Anaemic Premenopausal Women With Low Ferritin Levels And Fatigue

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Albina Nowak, MD · Academic / Other
• Sex: Female
• Age: 18 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

This study investigates the effect of intravenous iron substitution in non-anaemic premenopausal women with iron deficiency on: * Changes in the cerebral Dopamine (DA) receptor density after iron substitution, shown by brain PET * Reduction of fatigue and other neuropsychological symptoms after iron supplementation

Conditions

• Fatigue
• Iron-deficiency

Interventions

Type	Name	Description
DRUG	Iron Carboxymaltose	Single intravenous infusion within 20 min
DRUG	Sodium chloride 0.9%	Single intravenous infusion of 250 ml within 20 min

Timeline

• Start date: 2017-10-23
• Primary completion: 2019-08-31
• Completion: 2019-08-31
• First posted: 2017-10-10
• Last updated: 2017-10-13

Locations

1 site across 1 country: Switzerland