NCT03304171

Overall Diet Quality and Breast Cancer Risk

Diet Quality Scores and Risk of Incident Breast Cancer in Healthy Women

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 96,959 (actual)
• Sponsor: University of California, Irvine · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: —

Summary

The purpose of this study was to examine the relationship between indices of overall diet quality and incident breast cancer risk in a large prospective cohort of women.

Detailed description

This study examined the role of overall diet quality on the risk of developing invasive breast cancer among 96,959 women in the California Teachers Study, in which 4,826 women were diagnosed with breast cancer during follow-up (1995-2011). Participants' dietary habits were recorded at baseline (1995) using a 103-item Block95 Food Frequency Questionnaire to allow for the assessment of overall diet quality. Specifically, diet quality was characterized by the Alternate Mediterranean Diet (aMED), Alternative Healthy Eating Index-2010 (AHEI-2010), Dietary Approaches to Stop Hypertension (DASH), and Paleolithic Index scores. Associations between diet quality and the risk of developing breast cancer were examined using multivariate Cox proportional hazard regression models to provide hazard ratios and corresponding 95% confidence intervals.

Conditions

• Invasive Breast Cancer
• Incident Breast Cancer

Timeline

• Start date: 1995-10-01
• Primary completion: 2011-12-31
• Completion: 2011-12-31
• First posted: 2017-10-06
• Last updated: 2017-10-11