NCT03303391

Using Intradialytic Blood Pressure Slopes to Guide Ultrafiltration

Using Intradialytic Systolic Blood Pressure Slopes to Guide Ultrafiltration in Hemodialysis Patients: A Validation Study and Clinical Trial

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 14 (actual)
• Sponsor: University of Texas Southwestern Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This study is an open label randomized clinical trial that comparing intradialytic blood pressure slope-based ultrafiltration prescriptions to standard care in the chronic fluid management of maintenance hemodialysis patients. It also includes a cross sectional component evaluating the associations between intradialytic blood pressure slopes ascertained over 2 week periods with measurements of extracellular water/body weight obtained with multifrequency bioimpedance spectroscopy.

Conditions

• ESRD
• Extracellular Fluid Alteration
• Hypertension

Interventions

Type	Name	Description
OTHER	Intradialytic Blood Pressure Slope Based Ultrafiltration	Algorithmic Determination of ultrafiltration based on intradialytic blood pressure slopes calculated at the beginning of each month from the prior two weeks of dialysis treatments

Timeline

• Start date: 2017-11-01
• Primary completion: 2020-01-01
• Completion: 2020-01-01
• First posted: 2017-10-06
• Last updated: 2022-08-25
• Results posted: 2022-08-25

Locations

1 site across 1 country: United States