NCT03295500

On the Cyberknife Dose Fraction of Liver Cancer Treatment

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 657 (actual)
• Sponsor: Beijing 302 Hospital · Academic / Other
• Sex: All
• Age: 30 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The research aims to the primary hepatic carcinoma patients whose diameter of the single tumor is equal or less than 5cm.By supervising the changes of liver function, Child-Pugh score, ICG-R15 value, secondary reaction, incidence rate of RILD during and after the radiotherapy, meanwhile combining the outcome of the progression of disease and the condition of survival quality, the optimum proposal could be obtained and apply to clinic thus make the treatment safe, effective and personalized.

Conditions

• CyberKnife Radiosurgery

Interventions

Type	Name	Description
RADIATION	Dose fraction forms	The investigators divide the participants randomly into 3 groups by SPSS 19.0.Three groups participants receive the different dose fraction(49Gy/7f,54Gy/6f and 55Gy/5f),which also means different Biologic Equivalent Dose.Through the research,the investigators want to find out the optimum dose fraction method,which makes the treatment safe, effective and personalized.

Timeline

• Start date: 2017-11-01
• Primary completion: 2021-09-10
• Completion: 2021-09-24
• First posted: 2017-09-28
• Last updated: 2021-10-20

Locations

1 site across 1 country: China