NCT03292965

Monitoring of Postoperative Residual Neuromuscular Blockade in Laparoscopic Surgery

Monitoring of Postoperative Residual Neuromuscular Blockade in Laparoscopic Surgery: Comparison of Neostigmine and Sugammadex

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Seoul National University Bundang Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Compare the reversal effect of neostigmine and sugammadex using quantitative neuromuscular monitoring

Detailed description

At the end of surgery, decide the dosage of reversal referring to quantitative neuromuscular monitoring value (TOF). After the administration of reversal, the anesthesiologist who are going to manage the participant should not check the quantitative neuromuscular monitoring and determine the timing of extubation only with his (or her) judgement. After entering post-anaesthesia care unit (PACU) measure the TOF value and check the incidence of TOF ratio \> 0.9 between the neostigmine group and sugammadex group.

Conditions

• Neuromuscular Block, Residual

Interventions

Type	Name	Description
DRUG	Neostigmine	Referring to the randomisation allocation program, participants allocated to group neostigmine, administrate neostigmine as reversal
DRUG	Sugammadex	Referring to the randomisation allocation program, participants allocated to group sugammadex, administrate sugammadex as reversal

Timeline

• Start date: 2017-09-28
• Primary completion: 2017-11-29
• Completion: 2017-11-29
• First posted: 2017-09-26
• Last updated: 2018-10-09

Locations

1 site across 1 country: South Korea