NCT03291652

Morphology of Advanced Symptomatic Cerebral Plaques With High Embolic Potential

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 140 (estimated)
• Sponsor: Chinese University of Hong Kong · Academic / Other
• Sex: All
• Age: 30 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The study is to attain early recognition of the unstable plaques which have an imminent embolic risk in patients with intracranial atherosclerotic disease (IAD).

Detailed description

Potential candidates will undergo a cranial MRI and MR angiography. Patients who are found signal void in a relevant intracranial internal carotid artery or middle cerebral artery will proceed to a 30-minute TCD monitoring for MES an angiograms will be analyzed by investigators blind to subjects' clinical information. All recruited patients will receive standard medical therapy throughout the investigation period.

Conditions

• Ischemic Stroke
• Atheroscleroses, Cerebral

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	DSA/3DRA	DSA/3DRA

Timeline

• Start date: 2010-02-01
• Primary completion: 2026-12-23
• Completion: 2027-12-31
• First posted: 2017-09-25
• Last updated: 2026-02-24

Locations

1 site across 1 country: Hong Kong