Trials / Completed
CompletedNCT03290859
Race-Specific Propofol Titration to Effect for Procedural Sedation
Pragmatic Clinical Trial of Race-Specific Response to Propofol Infusion Titrated to Effect for Procedural Sedation During Endoscopy
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 2,780 (actual)
- Sponsor
- University of Florida · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
Prospectively evaluate newly established guidelines and make clinicians aware of inter-racial difference in propofol sensitivity.
Detailed description
The primary motivation in conducting this study is to conduct the implementation science, i.e., formalize and train, and retrain if needed, anesthesia providers in the standard practice of titrating infusion rate to effect and clinically evaluate the effect of race and ethnicity on propofol monotherapy sedation during GI endoscopy. The ultimate goal is to make it less likely that patients from races known to be sensitive to propofol experience inadvertent overdosing.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Titrate propofol monotherapy infusion to effect | Train anesthesia providers in a standardized protocol for titrating propofol infusion to effect. |
Timeline
- Start date
- 2018-01-05
- Primary completion
- 2019-02-05
- Completion
- 2019-02-05
- First posted
- 2017-09-25
- Last updated
- 2019-10-25
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT03290859. Inclusion in this directory is not an endorsement.