Trials / Unknown
UnknownNCT03289806
Effects of DHA on Post-operative Fibrosis of Trabulectomy Blebs in Glaucoma Surgery
Study of the Effects of Docosahexaneoic Acid (DHA) on Post-operative Fibrosis of Trabulectomy Blebs in Glaucoma Surgery
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 20 (estimated)
- Sponsor
- Centre Hospitalier Universitaire Dijon · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Post-operative fibrosis of trabulectomy blebs is a major cause of surgical failure leading to a renewed increase in intraocular pressure. The use of anti-metabolites over many years has made it possible to improve success rates for this surgery but these drugs have numerous adverse effects as they are toxic. Alternative therapies are thus necessary, and we believe that DHA could have antifibrotic effects on fibroblasts and could thus improve success rates in this surgery.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Samples of fibroblasts from Tenon's capsule |
Timeline
- Start date
- 2016-01-12
- Primary completion
- 2018-01-01
- Completion
- 2018-01-01
- First posted
- 2017-09-21
- Last updated
- 2017-09-21
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT03289806. Inclusion in this directory is not an endorsement.