Clinical Trials Directory

Trials / Unknown

UnknownNCT03289260

Adjuvant Anal Imiquimod Therapy in Anal HPV-lesions: AdAM-trial

Adjuvant Imiquimod Therapy to Reduce Recurrence Rate in Patients After Surgical Therapy of Anal HPV (Human Papilloma Virus)-Lesions

Status
Unknown
Phase
Phase 3
Study type
Interventional
Enrollment
200 (estimated)
Sponsor
Medical University Innsbruck · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

AdAM is a prospective, randomized, controlled, double-blinded, monocentric trial in patients receiving surgical therapy due to anal HPV infection. Aim of the study is to evaluate efficacy of combination therapy (surgical therapy + topical Imiquimod-therapy). It is planned to include 200 patients. 100 patients receive surgical therapy+ topical Imiquimod therapy, 100 patients receive surgical therapy + topical Placebo therapy

Conditions

Interventions

TypeNameDescription
DRUGImiquimod 5% creamPatients receive topical Imiquimod therapy for 12 weeks.
DRUGPlacebo creamPatients receive topical Doritin therapy for 12 weeks
PROCEDUREFulgurationSurgical Excision and Fulguration of condyloma

Timeline

Start date
2021-11-15
Primary completion
2024-11-15
Completion
2024-11-15
First posted
2017-09-20
Last updated
2020-09-23

Locations

1 site across 1 country: Austria

Source: ClinicalTrials.gov record NCT03289260. Inclusion in this directory is not an endorsement.