NCT03288662

Relationship Between Computed Tomography Manifestation and Histopathological Classification of Thymic Epithelial Tumors

Evaluate the Relationship Between Computed Tomography Manifestation and Histopathological Classification of Thymic Epithelial Tumors

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 2 (actual)
• Sponsor: Military Hospital 103 · Academic / Other
• Sex: All
• Age: 21 Years – 71 Years
• Healthy volunteers: Not accepted

Summary

the World Health Organization (WHO) has proposed a classification of histopathological thymic tumor and it significance in prognosis. Chest computed tomography (CT) is the most common method to evaluate thymic epithelial tumors before operation. Therefore, the question is to predict the histopathological type of thymic epithelial tumors before surgery based on CT-scan images , to help determine treatment strategy and prognosis. In Vietnam, there are no published literature on this issue.

Detailed description

1. Introduction: the World Health Organization (WHO) has proposed a classification of histopathological thymic tumor and it significance in prognosis. Chest computed tomography (CT) is the most common method to evaluate thymic epithelial tumors before operation. Therefore, the question is to predict the histopathological type of thymic epithelial tumors before surgery based on CT-scan images , to help determine treatment strategy and prognosis. In Vietnam, there are no published literature on this issue. 2. Materials and methods: 2.1. Cross-sectional descriptive study on 53 patients with diagnosed of thymoma by CT and had postoperative histopathology results as thymic epithelial tumors 2.2. Time and Place: in Departement of CTVS, Military Hospital 103, Vietnam from 10/2013 to 7/2017. 2.3. methods: * study in chest CT scan: * Measure the maximun diameter of the tumor * The contour: smooth contour or irregular contour * The shape: round, oval and plaque base on the ratio between long axis and short axis of the tumor * Some other characteristics: Degree of enhancement, Level of drug absorbed, Calcification, Invasion the local organs and Capsular destruction. * Histopathological study: based on the 2004 WHO classification: * Thymoma: type A, AB, B1, B2, B3 * Thymic carcinoma * Data processing: use software Epi Info 2000. 3. Expectation of results * Relationship between the size and histopathological type of thymic epithelial tumors. * Comparison of some characteristics of the tumor on preoperative chest CT scans and histopathological type of thymic epithelial tumors

Conditions

• Thymoma

Interventions

Type	Name	Description
OTHER	CT and histopathological classification	Cross-sectional descriptive study on 53 patients with diagnosed of thymoma by CT and had postoperative histopathology results as thymic epithelial tumors. Base on the characteristics in Chest CT scan in each postoperative histopathology results.

Timeline

• Start date: 2013-10-01
• Primary completion: 2017-07-01
• Completion: 2017-07-31
• First posted: 2017-09-20
• Last updated: 2017-09-20