NCT03287726

What is the Impact of Probiotics on Weight Loss Maintenance in Individuals With Obesity?

Evaluation of the Potential Impact of Probiotics on Weight Loss Maintenance in Individuals With Obesity

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 76 (actual)
• Sponsor: Norwegian University of Science and Technology · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Weight loss maintenance is the biggest challenge in obesity management, with the majority of weight-reduced individuals experiencing weight regain. The intake of probiotics has been shown to help in weight loss, but its potential in maximizing weight loss maintenance remains unknown. Therefore, the main aim of this study is to investigate the impact of probiotic consumption on weight loss maintenance. Secondary aims are to investigate if the intake of probiotics influences gut microbiota, cardio-metabolic profile, appetite and inflammatory markers.

Conditions

• Obesity

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	probiotics	NYCOPRO, a multistrain probiotic (7 strains of Lactobacilli and Bifidobacteria) sold in the Norwegian pharmacies. 2 capsules/day (one with lunch and one with dinner). 2 text messages daily as a reminder. Follow up meeting at ObeCe (St. Olavs hospital) every month with a research nurse, for weighing, blood pressure measurement and collection of probiotics dose for the following month.
DIETARY_SUPPLEMENT	placebo	Placebo 2 capsules/day (one with lunch and one with dinner). 2 text messages daily as a reminder. Follow up meeting at ObeCe (St. Olavs hospital) every month with a research nurse, for weighing, blood pressure measurement and collection of probiotics dose for the following month.

Timeline

• Start date: 2017-11-16
• Primary completion: 2020-12-31
• Completion: 2020-12-31
• First posted: 2017-09-19
• Last updated: 2021-03-04

Locations

1 site across 1 country: Norway