Trials / Terminated
TerminatedNCT03287063
Study Using Genomic, Histologic and Radiomic Analysis to Evaluate Regional Tumor Heterogeneity in Patients Undergoing Surgery for Newly Diagnosed Glioblastoma
A Prospective Study Using Genomic, Histologic and Radiomic Analysis to Evaluate Regional Tumor Heterogeneity in Patients Undergoing Surgery for Newly Diagnosed Glioblastoma
- Status
- Terminated
- Phase
- —
- Study type
- Observational
- Enrollment
- 6 (actual)
- Sponsor
- University of Michigan Rogel Cancer Center · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Glioblastomas (GBM) demonstrate in vivo genetic and histologic heterogeneity that can be non-invasively identified using imaging phenotypes that identify regionally distinct areas of tumor with genetic alterations that drive tumor resistance pathways. The researchers propose a unique approach to assess initial GBM heterogeneity by performing histological and genomic analysis of biopsies targeted by advanced MRI before treatment.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Tumor Biopsy | Stereotactic biopsies will be performed prior to resection. |
Timeline
- Start date
- 2018-07-05
- Primary completion
- 2020-03-23
- Completion
- 2020-03-23
- First posted
- 2017-09-19
- Last updated
- 2025-07-01
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT03287063. Inclusion in this directory is not an endorsement.