NCT03286621

Development of Eye-tracking Based Markers for Autism in Young Children

Evaluation of Five Different Eye-tracking Paradigms to Determine Autism in Young Children

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 70 (actual)
• Sponsor: University of Electronic Science and Technology of China · Academic / Other
• Sex: All
• Age: 12 Months – 10 Years
• Healthy volunteers: Accepted

Summary

The main aim of the present study is to examine eye-tracking based markers for social processing deficits in children with autism spectrum disorder (ASD). To this end a battery of five eye-tracking paradigms will be administered to young children with ASD and typically developing children. To additionally evaluate the specificity of the eye-tracking markers a group of children with disorders of delayed development other than ASD will be included.

Detailed description

During an initial screening session all participants will undergo the Autism Diagnostic Observation Schedule (ADOS). ASD-related symptomatology and levels of impairments will be further characterized using the Social Responsibilities Scale 2 (SRS 2), Caregiver Strain Questionnaire (CSQ), Aberrant Behavior Checklist (ABC), Social Communication Questionnaire (SCQ), and Repetitive Behaviour Scale Revised (RBS-R). Subsequently all participants will be administered the following eye-tracking paradigms: (1) dynamic social and non-social visual preference paradigm during which dynamic geometric images (DGI) and dynamic social images (DSI) will be presented, (2) non-biological versus biological motion paradigm, (3) social attention and sharing of enjoyment paradigm, (4) preference for real versus schematic emotional face stimuli paradigm during which photographs of human faces and emoticons will be presented, (5) shared social attention and gaze direction paradigm.

Conditions

• Autism Spectrum Disorder

Interventions

Type	Name	Description
OTHER	Administration of five eye-tracking paradigms	All subjects will undergo the battery of five eye-tracking paradigms to determine potential markers for autism.

Timeline

• Start date: 2017-09-09
• Primary completion: 2018-02-28
• Completion: 2018-02-28
• First posted: 2017-09-18
• Last updated: 2018-10-29

Locations

1 site across 1 country: China