NCT03284814

Bioavailability Study of CoQ10 Formulations in Healthy Elderly Adults

Single-dose and Multiple-dose Comparative Bioavailability Study of Three CoQ10 Formulations in Healthy Elderly Adults

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 21 (actual)
• Sponsor: Institute of Nutrition, Slovenia (Nutris) · Academic / Other
• Sex: All
• Age: 65 Years – 74 Years
• Healthy volunteers: Accepted

Summary

The single-center, randomized, open-label, three-period crossover bioavailability study will include 21 subjects who will test three CoQ10 formulations. Subjects will test 3 formulations of single dose CoQ10 within first 3 weeks to assess bioavailability, which will be followed with 2 weeks of continuous administration of one of study formulations to demonstrate and assesse multiple-dose profile of CoQ10.

Conditions

• Bioavailability of Coenzyme Q10

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Single dose intervention with Standard product (SP)	hard capsules, 100 mg
DIETARY_SUPPLEMENT	Single dose intervention with Comparative product (CP)	soft-gel capsules, 100 mg
DIETARY_SUPPLEMENT	Single dose intervention with Investigational product (IP)	syrup, 100 mg
DIETARY_SUPPLEMENT	Multiple dose intervention with Standard product (SP)	hard capsules, 100 mg - 14 days
DIETARY_SUPPLEMENT	Multiple dose intervention with Comparative product (CP)	soft-gel capsules, 100 mg - 14 days
DIETARY_SUPPLEMENT	Multiple dose intervention with Investigational product (IP)	syrup, 100 mg - 14 days

Timeline

• Start date: 2017-08-29
• Primary completion: 2017-10-20
• Completion: 2017-10-20
• First posted: 2017-09-15
• Last updated: 2019-03-20

Locations

3 sites across 1 country: Slovenia