Trials / Unknown
UnknownNCT03284294
Influence of Vitamin D Supplementation on Serum BDNF Level and Cognitive Function in Schizophrenia
The Influence of Vitamin D Supplementation on Serum Brain Derived Neurotrophic Factor Level and Cognitive Function in Schizophrenia Treated With Atypical Antipsychotic
- Status
- Unknown
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- Sponsor
- Universitas Padjadjaran · Academic / Other
- Sex
- Male
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Not accepted
Summary
The objective of the study is to evaluate the influence of vitamin D supplementation on Serum Brain Derived Neurotrophic Factor level and cognitive function in schizophrenia treated with atypical antipsychotic. Methods: The investigator will use randomized controlled trial design. 40 chronic schizophrenia patients with vitamin D insufficiency or deficiency treated with atypical antipsychotic, will be randomly assign (1:1 ratio) to receive either daily oral cholecalciferol 2000 IU or placebo for 8 weeks. Assessment of BDNF serum and cognitive function will be performed at baseline and after 8 weeks period.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Cholecalciferol | cholecalciferol 2000 IU oral daily for 8 weeks |
| DRUG | Placebo | Oral placebo daily for 8 weeks |
Timeline
- Start date
- 2020-04-15
- Primary completion
- 2020-08-01
- Completion
- 2020-12-01
- First posted
- 2017-09-15
- Last updated
- 2020-04-02
Source: ClinicalTrials.gov record NCT03284294. Inclusion in this directory is not an endorsement.