NCT03284151

Focused Stereotactic Radiation Treatment of Prostatic Adenocarcinoma

Robotic and Focused Stereotactic Radiation Treatment of Good Prognosis Prostatic Adenocarcinoma

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 26 (actual)
• Sponsor: Centre Francois Baclesse, Luxembourg · Academic / Other
• Sex: Male
• Age: —
• Healthy volunteers: Not accepted

Summary

Focused stereotactic radiation treatment of localized prostatic adenocarcinoma. in order to quantify the delay between the focused treatment and the salvage procedure.

Detailed description

Focused stereotactic radiation treatment of localized prostatic adenocarcinoma. in order to quantify the delay between the focused treatment and the salvage procedure. Second objectives : objectives: prostate-specific antigen (PSA) response, MRI response, toxicity (CTCAEv4), quality of life (International Prostate Symptom Score (IPSS) and The International Index of Erectile Function (IIEF5) scores). Method At first: Multiparametric Magnetic resonance imaging (MRI) - 12 biopsies within the whole gland. Placement under endorectal ultrasound control of 4 fiducials at least 2 cm spaced. Treatment : CyberKnife radiation treatment delivering 36.25 Gy in 5 fractions, in 10 days. Tracking using the 4 fiducials. Critical organs: Rectal and bladder wall: V35\<2cc. Bladder neck and urethra: V35\<1cc. Salvage treatments: in such a context, salvage surgery or salvage intensity modulation radiation therapy (IMRT) treatments can in theory remain valid and safe options.

Conditions

• Prostate Cancer

Interventions

Type	Name	Description
RADIATION	Cyberknife

Timeline

• Start date: 2015-01-01
• Primary completion: 2020-01-01
• Completion: 2023-01-01
• First posted: 2017-09-15
• Last updated: 2022-06-22

Locations

1 site across 1 country: Luxembourg