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Active Not RecruitingNCT03282344

A Study of NKTR-214 in Combination With Nivolumab in Patients With Metastatic and/or Locally Advanced Sarcoma

A Pilot Study of NKTR-214 and Nivolumab in Selected Patients With Locally Advanced/Metastatic Sarcoma (CA209-9EM)

Status
Active Not Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
88 (actual)
Sponsor
Memorial Sloan Kettering Cancer Center · Academic / Other
Sex
All
Age
12 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to test any good and bad effects of the combination of study drugs called NKTR-214 and nivolumab.

Conditions

Interventions

TypeNameDescription
DRUGNKTR-2140.006mg/kg IV on day 1 and every 3 weeks thereafter will be an intravenous (IV) infusion administered over 30 (±5) minutes every 3 weeks.
DRUGNivolumab360mg (flat dose) IV infusion administered over 30 (±5) minutes every 3 weeks.

Timeline

Start date
2017-09-12
Primary completion
2026-09-01
Completion
2026-09-01
First posted
2017-09-13
Last updated
2025-10-01

Locations

2 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03282344. Inclusion in this directory is not an endorsement.