NCT03280615

Omega 3 Fatty Acids in Patients With Chronic Renal Disease

Effects of the Supplementation With Omega 3 Fatty Acids in Patients With Chronic Renal Disease

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: University of Chile · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

To study the tolerance and efficacy of an omega 3 fatty acids supplement on renal and vascular function and inflammatory parameters in patients with chronic renal disease

Detailed description

In a double blind trial in patients with chronic renal disease, the effects of a 3.7 g supplement of docosahexanoic and eicosapentanoic acids or a supplement of a similar dose of corn oil during 12 weeks, will be assessed on the following parameters: 1. Urine albumin excretion 2. Renal function measured with serum creatinine, cystatin C and beta-2 microglobulin 3. Carotid intima media thickness and pulse wave velocity 4. Inflammation status assessed measuring serum levels of C reactive protein and interleukin 6 5. Metabolic control of diabetes 6. Serum lipid levels

Conditions

• Renal Insufficiency, Chronic

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Omega 3 fatty acids	Omega 3 fatty acids will be provided in a dose of 3.7 g/day, that should be enough to rise red blood cell levels of eicosapentanoic and docosahexanoic acids
DIETARY_SUPPLEMENT	Corn oil	Corn oil will be the placebo comparator for omega 3 fatty acids supplement

Timeline

• Start date: 2017-09-20
• Primary completion: 2018-10-31
• Completion: 2018-10-31
• First posted: 2017-09-12
• Last updated: 2019-09-09
• Results posted: 2019-09-09

Locations

1 site across 1 country: Chile