NCT03280316

Efficacy Comparison Between Different Management Strategies for Consistent OAB in Patients With SVMs After Surgery

Efficacy Comparison Between Different Management Strategies for Consistent Overactive Bladder (OAB) in Patients With Spinal Vascular Malformations After Surgery

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Xuanwu Hospital, Beijing · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The investigators' goal is to compare the efficacy of three different management strategies (sacral neuromodulation, botulinum toxin, M receptor antagonist) in treating consistent OAB in patients with SVMs after surgery.

Detailed description

Spinal Vascular malformations (SVMs) are complex neurosurgical lesions and account for 3%-4% of all intradural spinal cord mass lesions, which can influence the function of bladder. The investigators' goal is to compare the efficacy of three different management strategies (sacral neuromodulation, botulinum toxin, M receptor antagonist) in treating consistent OAB (Overactive Bladder) in patients with SVMs after surgery.

Conditions

• Spinal Vascular Disorder Nos
• Overactive Bladder

Interventions

Type	Name	Description
PROCEDURE	surgery	patients with SVMs receive surgery
PROCEDURE	sacral neuromodulation	sacral neuromodulation (SNM) with InterStimTM
PROCEDURE	botulinum toxin A injection	BOTOX
DRUG	M receptor antagonist	Tolterodine

Timeline

• Start date: 2023-01-01
• Primary completion: 2023-10-01
• Completion: 2023-12-01
• First posted: 2017-09-12
• Last updated: 2020-04-29