NCT03278756

Online Cognitive Control Training for Remitted Depressed Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 68 (actual)
• Sponsor: University Ghent · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This study evaluates the effectiveness of an internet-delivered cognitive control training as a preventive intervention for remitted depressed patients. Half of the participants will receive a cognitive control training, while the other half will receive a low cognitive load training that acts as an active control condition.

Detailed description

Prospective studies have linked impaired cognitive control to increased cognitive vulnerability for future depression. Importantly, experimental studies indicate that cognitive control training can be used to reduce rumination and depressive symptomatology in MDD (major depressive disorder) and RMD (remitted depressed) samples. Provided that remitted depressed patients form a high-risk group for developing future depressive episodes, the current study will explore whether an internet-delivered cognitive control training can be used to reduce vulnerability for future depression in remitted depressed patients. A computer training, consisting of 10 sessions of 15 minutes each, will be administered to participants, which are remitted depressed patients. This training can either be a cognitive control training, using an adaptive paced auditory serial addition task, or an active control training, with a low cognitive load task. Dependent variables will be assessed pre- and post-training, as well as 3 and 6 months after the training, and consist of depressive symptomatology, related variables and cognitive control measures.

Conditions

• Major Depression in Remission

Interventions

Type	Name	Description
BEHAVIORAL	Cognitive control training	10 sessions of an adaptive paced auditory serial addition task, each lasting 15 minutes, over the course of two weeks.
BEHAVIORAL	Active control training	10 sessions of an low cognitive load task, each lasting 15 minutes, over the course of two weeks.

Timeline

• Start date: 2017-09-01
• Primary completion: 2019-03-13
• Completion: 2019-03-13
• First posted: 2017-09-12
• Last updated: 2022-11-09

Locations

1 site across 1 country: Belgium