NCT03276104

Late In-the-bag intraOcular Lens dislocatioN Surgery

Late In-the-bag intraOcular Lens dislocatioN Surgery: A Randomized Clinical Trial (LION Trial)

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Oslo University Hospital · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Overall aim of the study is to compare the safety and efficacy of two different surgical methods to treat Late In-the-bag intraocular lens dislocation.

Detailed description

Cataract is a condition of unclear lens that cause poor vision. The only treatment is surgery where the blurred biological lens is replaced with an artificial clear lens (IOL). Most people who operate achieve full vision. Nevertheless, serious complications may occasionally occur, and one of these is dislocation of the entire complex with IOL and lens capsule. This requires surgical treatment. In this study the investigators want to compare two different surgical methods used in late dislocation of IOL inside the capsule after cataract surgery. Patients will be randomly affiliated to either the suturing of existing IOL / capsule complex, or lens exchange to an IOL fixed to the iris. The focus of the trial will be especially on complications and other eye changes in the early stages of surgery. Today, little data is available on these topics, and the investigators believe that new knowledge can bring us closer to a response to preferred operating techniques and an optimal drug drop regime for the patient group.

Conditions

• Intraocular Lens Dislocation

Interventions

Type	Name	Description
PROCEDURE	IOL repositioning	Intraocular lens repositioning by scleral suturing
PROCEDURE	IOL exchange	Intraocular lens exchange with retropupillary iris-claw lens

Timeline

• Start date: 2017-09-09
• Primary completion: 2020-11-01
• Completion: 2022-12-01
• First posted: 2017-09-08
• Last updated: 2019-04-17

Locations

1 site across 1 country: Norway