Clinical Trials Directory

Trials / Completed

CompletedNCT03275454

A Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple- Dose BIVV009 in Participants With Chronic Immune Thrombocytopenia (ITP)

A Phase 1 Safety, Tolerability, and Pharmacokinetics & Pharmacodynamics Study of Multiple- Dose BIVV009 in Patients With Chronic Immune Thrombocytopenia (ITP)

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
12 (actual)
Sponsor
Bioverativ, a Sanofi company · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to explore the safety, preliminary clinical benefit, and activity of BIVV009 in patients with chronic immune thrombocytopenia.

Conditions

Interventions

TypeNameDescription
DRUGBIVV009 6.5 gramsParticipants who weigh less than 75 kilogram (kg) will receive fixed doses of 6.5 grams of BIVV009.
DRUGBIVV009 7.5 gramsParticipants who weigh 75 kg or more will receive fixed doses of 7.5 grams of BIVV009.

Timeline

Start date
2017-08-14
Primary completion
2021-02-16
Completion
2021-02-16
First posted
2017-09-07
Last updated
2023-05-18

Locations

5 sites across 3 countries: United States, Germany, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT03275454. Inclusion in this directory is not an endorsement.