NCT03274167

Efficacy of Gabapentin in Alcohol Dependency Treatment

Efficacy of Gabapentin in Alcohol Dependency Treatment: a Double-blinded Randomized Placebo-controlled Trial

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 112 (actual)
• Sponsor: Chulalongkorn University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The study aims to study the effect of gabapentin on the number of alcohol drinking days and heavy drinking days in the Thai clinical alcohol-dependent population by using the double-blinded randomized controlled approach. One-hundred and twelve individuals with alcohol dependence were randomly assigned equally into two groups including treatment with gabapentin and placebo. Thirty-four patients (30.3%) completed the study protocol, i.e. treatment with gabapentin at least 300 mg per day or placebo orally once a day for twelve weeks. Pattern of alcohol drinking were obtained from the timelime followback. Drinking behaviors were compared between the two groups by poisson repeated measures model.

Conditions

• Alcohol Drinking
• Heavy Drinking

Interventions

Type	Name	Description
DRUG	Gabapentin 300mg
DRUG	Placebo oral capsule

Timeline

• Start date: 2012-01-01
• Primary completion: 2014-12-01
• Completion: 2014-12-01
• First posted: 2017-09-06
• Last updated: 2017-09-06

Locations

1 site across 1 country: Thailand