NCT03272152

Comprehensive DNA Methylation Profiling in Crohn's Disease

Comprehensive DNA Methylation Profiling of Inflammatory and Non-Inflammatory Mucosa in Crohn's Disease

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 14 (estimated)
• Sponsor: Jinling Hospital, China · Academic / Other
• Sex: Male
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Previous studies have indicated that abnormal DNA methylation frequently occurs in the mucosa in Crohn's disease. Comprehensive DNA methylation profiling of the inflamed and non-inflamed ileal mucosa of patients with Crohn's disease was performed. Genome-wide DNA methylation was determined using the Illumina HumanMethylation 850k BeadChip.

Conditions

• Crohn Disease
• Methylation
• Illumina Human Methylation 850k BeadChip

Interventions

Type	Name	Description
GENETIC	Genome-wide DNA methylation	Genome-wide DNA methylation was determined using the Infinium Human Methylation 850K BeadChip.

Timeline

• Start date: 2017-01-01
• Primary completion: 2017-09-30
• Completion: 2017-09-30
• First posted: 2017-09-05
• Last updated: 2017-09-05

Locations

1 site across 1 country: China