NCT03270579

A Study to Investigate the Regional Brain Kinetics of the Positron Emission Tomography Ligand [18F]JNJ-64511070

An Open-Label Study to Investigate the Regional Brain Kinetics of the Positron Emission Tomography Ligand [18F]JNJ-64511070

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 8 (actual)
• Sponsor: Janssen Research & Development, LLC · Industry
• Sex: Male
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The main purpose of the study is to measure the whole-body distribution and radiation dosimetry of \[18F\]JNJ-64511070 in healthy male participants by positron emission tomography (PET) (Part A); and to measure the uptake, binding, distribution, and washout of \[18F\]JNJ-64511070 in the brain of healthy male participants by PET and to model tissue specific kinetics of \[18F\]JNJ-64511070 with the appropriate arterial input function (IF) (Part B).

Conditions

• Healthy

Interventions

Type	Name	Description
DRUG	[18F]JNJ-64511070	An IV injection of 185 MBq \[18F\]JNJ-64511070 will be administered.

Timeline

• Start date: 2017-09-12
• Primary completion: 2018-02-06
• Completion: 2018-02-06
• First posted: 2017-09-01
• Last updated: 2025-04-27

Locations

1 site across 1 country: Belgium