NCT03268759

Development of Reward Processing in Prenatally Exposed Adolescents and Young Adults

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 78 (actual)
• Sponsor: Yale University · Academic / Other
• Sex: All
• Age: 18 Years – 20 Years
• Healthy volunteers: Accepted

Summary

Reward processing will be examined in prenatally exposed emerging adults in a longitudinal design. Participants will be followed for one year to see if neural markers of reward processing prospectively predict risk-taking behavior.

Detailed description

This cohort will be drawn from a pre-existing cohort of individuals recruited as part of an already existing study, and who have been followed since birth. Reward processing will be measured in two temporally close testing sessions involving two methodologies, electrophysiology and fMRI. Information will also be collected pertaining to experimental and problematic drug use, as well as information about mood, at the recording sessions. Drug use and mood information will then be collected once again in quarterly follow-up sessions for one year. The goal is to examine if PCE status and reward processing are risk factors for problematic drug abuse and risky behaviors in emerging adulthood, and if these factors interact to increase such risk.

Conditions

• Pre-natal Cocaine Exposure
• Risk-Taking

Interventions

Type	Name	Description
OTHER	fMRI	Observation of neural markers of reward processing

Timeline

• Start date: 2017-09-15
• Primary completion: 2020-09-14
• Completion: 2020-09-14
• First posted: 2017-08-31
• Last updated: 2021-05-04

Locations

1 site across 1 country: United States