NCT03263962

Canrenone Effects on Cardiovascular Mortality in Patients With Congestive Heart Failure (the Coffee-it Study)

Canrenone Effects on Cardiovascular Mortality in Patients With Congestive Heart Failure: the Coffee-it Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 502 (actual)
• Sponsor: University of Pavia · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: —

Summary

To evaluate canrenone effects compared to other therapies on cardiovascular mortality in patients with congestive heart failure and preserved systolic function after 12 years of evaluation.

Detailed description

The investigators will verify patients with cardiac heart failure (CHF) and preserved systolic function and each patient must have all clinical evaluation through basal measurements of blood pressure, heart rate, biochemical tests, and color Doppler echocardiographic parameters for at least 12 years. The investigators will evaluate the effects of an aldosterone antagonist as canrenone compared to a group without canrenone and the investogators will verify how many patients reported cardiovascular mortality or will survive.

Conditions

• Cardiac Heart Failure Patients

Interventions

Type	Name	Description
DRUG	Canrenone	Evaluation of canrenone therapy in patients with CHF

Timeline

• Start date: 2017-07-13
• Primary completion: 2017-09-10
• Completion: 2017-11-30
• First posted: 2017-08-28
• Last updated: 2018-02-05

Locations

1 site across 1 country: Italy