NCT03263884

Repetitive Transcranial Magnetic Stimulation and the Development of Ongoing Muscle Pain

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Aalborg University · Academic / Other
• Sex: All
• Age: 21 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The main purpose of the study is to assess the mechanisms of repeated sessions of repetitive trancranial magnetic stimulation (rTMS) applied on left dorsolateral prefrontal cortex on the development of pain in a prolonged muscle pain model.

Detailed description

This study aims to investigate whether i) rTMS of left DLPFC will reduce the severity and duration of experimentally induced muscle pain when a 5-day course of treatment is given immediately following an initial nerve growth factor (NGF) injection; ii) the analgesic effects of left DLPFC rTMS will be related to an improved cognitive network function as assessed by electroencephalography (EEG).

Conditions

• Pain Relief

Interventions

Type	Name	Description
DEVICE	Repetitive trancranial magnetic stimulation (rTMS) group	Repetitive trancranial magnetic stimulation is applied on the dorsolateral prefrontal cortex. The protocol consists on 20 minutes of 10Hz stimulation, 5 seconds on, 10 seconds off, at 110% RMT, for a total of 4000 pulses.
DEVICE	Sham group	A sham coil is used to mimic the clicking sound of the trancranial magnetic coil and skin stimulation.

Timeline

• Start date: 2017-08-01
• Primary completion: 2017-11-30
• Completion: 2018-02-28
• First posted: 2017-08-28
• Last updated: 2018-03-05

Locations

1 site across 1 country: Denmark