Clinical Trials Directory

Trials / Completed

CompletedNCT03261635

Ranibizumab Plus Indomethacin

Prospective Randomized Controlled Trial of Combination Ranibizumab and Indomethacin for Exudative Age-Related Macular Degeneration

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
58 (actual)
Sponsor
Università degli Studi di Brescia · Academic / Other
Sex
All
Age
40 Years
Healthy volunteers
Not accepted

Summary

To evaluate whether indomethacin eyedrops plus intravitreal ranibizumab (IVR) provides additional benefit over IVR monotherapy for treatment of choroidal neovascularization (CNV) in age-related macular degeneration.

Conditions

Interventions

TypeNameDescription
DRUGRanibizumab Injectionpatients received monthly 0.5 mg ranibizumab intravitreal injections for 3 months, after which monthly injections were administered pro re nata
DRUGIndomethacinpatients self-administered one drop of indomethacin 0.5% eye drops three times a day for 12 months

Timeline

Start date
2016-01-07
Primary completion
2016-12-07
Completion
2017-07-25
First posted
2017-08-25
Last updated
2017-08-25

Source: ClinicalTrials.gov record NCT03261635. Inclusion in this directory is not an endorsement.