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Trials / Active Not Recruiting

Active Not RecruitingNCT03261102

TDM Guided Early Optimization of ADAL in Crohn's Disease

Therapeutic Drug Monitoring Guided Early Optimization of Adalimumab in Crohn's Disease; A Randomized Open Label Study

Status
Active Not Recruiting
Phase
N/A
Study type
Interventional
Enrollment
200 (estimated)
Sponsor
waqqas.afif · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

To investigate the influence of early therapeutic drug monitoring and dose optimization on disease outcome in Crohn's patients treated with Adalimumab.

Detailed description

This is an investigator initiated randomized open label study. This study is designed to compare whether increasing the dose of adalimumab based on the level the drug in the blood to a target level early in the treatment course would lead to better outcomes for patients as compared to the standard doses.

Conditions

Interventions

TypeNameDescription
BIOLOGICALAdalimumab

Timeline

Start date
2017-01-17
Primary completion
2025-01-15
Completion
2025-06-01
First posted
2017-08-24
Last updated
2025-05-25

Locations

6 sites across 1 country: Canada

Source: ClinicalTrials.gov record NCT03261102. Inclusion in this directory is not an endorsement.

TDM Guided Early Optimization of ADAL in Crohn's Disease (NCT03261102) · Clinical Trials Directory