NCT03257514

Effect of Alpha Lipoic Acid on Uterine Scar Healing After Cesarean Section

Assessing The Effect of Alpha Lipoic Acid on Uterine Scar Healing After Cesarean Section by Using Saline Contrast Sonohysterography

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 102 (actual)
• Sponsor: Ain Shams University · Academic / Other
• Sex: Female
• Age: 18 Years – 35 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to evaluate the efficacy of alpha lipoic acid on uterine scar healing after cesarean section by using saline contrast sonohysterography

Detailed description

This is a triple blind randomized placebo controlled prospective clinical trial that will be conducted in Ain Shams University Maternity Hospital. in which a consecutive series of participant attending emergency room 102 women undergoing cesarean section for the first time will be randomized into two groups. Group A (Study group): 51 women will receive alpha lipoic acid drug ( 600 mg twice daily) for 6 weeks after cesarean section and saline sonohysterography will be done after that. Group B (Control group): 51 women will receive a placebo drug twice daily for 6 weeks after cesarean section and saline sonohysterography will be done after that.

Conditions

• Cesarean Section; Dehiscence
• Cesarean Scar Niche

Interventions

Type	Name	Description
DRUG	alpha lipoic acid drug (thioctic acid acid)	Alpha lipoic acid has anti-inflammatory, antioxidant effects and plays a role in wound healing process.
DRUG	Placebo Oral Tablet	placebo oral drug have the same shape of thiotacid tablet

Timeline

• Start date: 2017-06-01
• Primary completion: 2018-01-01
• Completion: 2018-02-01
• First posted: 2017-08-22
• Last updated: 2018-03-08

Locations

1 site across 1 country: Egypt