Clinical Trials Directory

Trials / Completed

CompletedNCT03255590

Can we Train Patients With Chronic Stroke Out of Abnormal Hand Synergy?

Training and Non-Invasive Brain Stimulation in Chronic Stroke Reduce Abnormal Hand Synergy

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
20 (actual)
Sponsor
Johns Hopkins University · Academic / Other
Sex
All
Age
21 Years – 99 Years
Healthy volunteers
Not accepted

Summary

This study plans to determine whether training can change abnormal flexion synergy in chronic stroke patients.

Detailed description

The aim of the current study is to investigate whether motor training in chronic stroke patients can change their abnormal flexion synergy. The investigators will study chronic stroke patients , who are defined as patients that sustained a stroke at least 6 months prior to our testing date. Three functional aspects of each finger will be tested: maximal voluntary contraction (MVC), finger dexterity, and hand posture. Prior to intervention, participants will have a baseline assessment including clinical tests, MVC, the individuation task, and the configuration task. Following the baseline assessment patients will receive intervention, training on the configuration task for 5 consecutive days. On the sixth day and as a one week follow-up after, subjects will have a post-intervention assessment containing the same tests performed in baseline. This design will allow us to determine speed and accuracy during the configuration task, the individuation index, and possible changes in abnormal flexion synergy. We initially registered the study as two arms (anodal tDCS and sham tDCS groups) but decided to make it one arm due to the number of participants we were able to recruit.

Conditions

Interventions

TypeNameDescription
BEHAVIORALConfiguration taskTraining the impaired hand on a configuration task

Timeline

Start date
2017-03-03
Primary completion
2020-12-30
Completion
2020-12-30
First posted
2017-08-21
Last updated
2021-11-08

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT03255590. Inclusion in this directory is not an endorsement.