Trials / Completed
CompletedNCT03254121
Genome Studies of Hepatocellular Carcinoma Developed in Hepatitis C Patients With Sustained Virological Response
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 93 (actual)
- Sponsor
- Karolinska Institutet · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
In this international collaboration study, the research group will analyze somatic mutations of hepatocellular carcinoma (HCC) developed after sustained virological response (SVR) in patients treated with hepatitis C (HCV) therapy
Detailed description
Method Paired liver tissue samples will be collected from the tumour sections and also from the adjacent non-tumour tissues, for comparison in each individual. The tissues have been collected as part of routine clinical work/other studies, by liver biopsies or at liver resection/liver transplantation. Data regarding the patient characteristic will be collected. Whole genome sequencing analyses are planned to be performed.
Conditions
Timeline
- Start date
- 2017-01-01
- Primary completion
- 2020-09-01
- Completion
- 2020-09-01
- First posted
- 2017-08-18
- Last updated
- 2021-02-18
Locations
1 site across 1 country: Sweden
Source: ClinicalTrials.gov record NCT03254121. Inclusion in this directory is not an endorsement.