NCT03253809

Survey of QRS Frequency at Various Left Ventricular Pacing Sites for Cardiac Resynchronization

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 14 (actual)
• Sponsor: The Cleveland Clinic · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

LV pacing at various sites with recording of ECG and subsequent signal analysis at different sites.

Detailed description

During routine cardiac resynchronization pacemaker or implantable defibrillator (ICD) implantation (including de-novo and upgrade from standard device, additional pacing within 3 different coronary veins will be performed in combination with a previously implanted right ventricular pacing or ICD lead. The resulting electrocardiogram signal will be analyzed afterwards. A time-frequency analysis (TFA) of several ECG leads at each paced site will be performed and compared. The results of the TFA analysis will not be used to select pacing lead location in this study. The patient will then receive the left ventricular pacing lead in the standard manner.

Conditions

• Cardiomyopathies
• Congestive Heart Failure

Interventions

Type	Name	Description
DEVICE	Biotronik Vision Guidewire	The apical, mid ventricular and basal sites within the anterior,posterior and lateral coronary sinus branch veins will be paced.

Timeline

• Start date: 2017-07-12
• Primary completion: 2021-11-02
• Completion: 2021-11-02
• First posted: 2017-08-18
• Last updated: 2022-03-09
• Results posted: 2022-03-09

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study