NCT03252704

Post-prandial Glycemic Response to Fiber in Healthy Adults

Post-prandial Glucose and Insulin Response to High-fiber Muffin Top Containing Resistant Starch in Healthy Adults

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 28 (actual)
• Sponsor: Ingredion Incorporated · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This randomized, double-blind, comparator controlled trial evaluated the blood glucose and insulin responses in healthy adults, after consuming a high fiber or low fiber muffin top.

Detailed description

The fiber administered in this trial is a resistant starch type 4 derived from high-amylose maize starch. This product is high in dietary fiber (70% total dietary fiber (TDF), AOAC 2009.01 method) and can be used in a variety of bakery applications. The objective of this study was to evaluate the post-prandial blood glucose and insulin responses of healthy adults (n=28) after consuming a muffin top made with resistant starch or control muffin top, in a randomized, double-blind, crossover study. The muffin tops were matched for total weight, total carbohydrate, sugars, protein, and fat. During each 24-hour study period, subjects consumed a standard evening meal, fasted for 12 hours, and arrived at the study clinic the following morning. Serum glucose, serum insulin, and capillary glucose were measured after muffin top consumption. The subjects completed a seven day washout between treatments.

Conditions

• Glucose, High Blood
• Glucose, Low Blood
• Meals

Interventions

Type	Name	Description
OTHER	resistant starch (high fiber muffin top)	Muffin top contained 11 g of fiber per portion
OTHER	control (low fiber muffin top)	Muffin top contained 1 g of fiber per portion

Timeline

• Start date: 2016-03-31
• Primary completion: 2016-10-31
• Completion: 2016-10-31
• First posted: 2017-08-17
• Last updated: 2017-08-21