NCT03252119

High Flow Oxygen Therapy vs Standard Care in Infants With Viral Bronchiolitis

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 28 (actual)
• Sponsor: Chris Hani Baragwanath Academic Hospital · Academic / Other
• Sex: All
• Age: 1 Month – 2 Years
• Healthy volunteers: Not accepted

Summary

A randomized control trial of 130 infants admitted to the paediatric high care admission ward will be enrolled, and randomized to either "high flow humidified oxygen" or "standard therapy".

Detailed description

A randomized control trial of 130 infants admitted to the paediatric high care admission ward will be enrolled. Infants between 1 month and 2 years of age who fulfill criteria for enrollment shall be considered eligible. Informed consent from parents or legal guardians shall be obtained. Infants shall be randomized to either "standard therapy" or "high flow humidified oxygen". Measurements of heart rate, respiratory rate, work of breathing (Tal score and WCAS), oxygen saturation and oxygen requirements shall be recorded.

Conditions

• Bronchiolitis, Viral

Interventions

Type	Name	Description
DEVICE	High flow humidified oxygen therapy	application of high flow humidified oxygen therapy at 2l/kg/min

Timeline

• Start date: 2017-06-01
• Primary completion: 2018-08-31
• Completion: 2018-08-31
• First posted: 2017-08-17
• Last updated: 2019-07-24

Locations

1 site across 1 country: South Africa