NCT03245957

HDL Dysfunction During the Acute Stage of Stroke

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 112 (estimated)
• Sponsor: Centre Hospitalier Universitaire de la Réunion · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The study investigates the effect of plasma myeloperoxidase (MPO) concentrations on HDL dysfunction during the acute stage of ischemic and haemorrhagic strokes.

Detailed description

MRI or CT scan are used to confirm the diagnosis of haemorrhagic, ischemic and mimick stroke. Plasma anf HDL-MPO concentrations, as well as potent HDL dysfunction, are compared in the 3 cases. The investigators hypothesis is that MPO concentrations and subsequent HDL dysfunction could be higher in ischemic strokes than in haemorrhagic ones. MPO could be a examined as a potent marker of early stage of ischemic stroke. Plasma MPO levels could also be discriminant regarding the mimick strokes in patient exhibiting stroke clinical picture.

Conditions

• Stroke, Acute

Interventions

Type	Name	Description
OTHER	Ischemic stroke	Patients with acute stage of stroke clinical picture, with ischemic, haemorrhagic or mimick stroke diagnosed using MRI or CT scan
OTHER	Haemorrhagic stroke	Patients with acute stage of stroke clinical picture, with ischemic, haemorrhagic or mimick stroke diagnosed using MRI or CT scan

Timeline

• Start date: 2017-10-20
• Primary completion: 2019-10-01
• Completion: 2020-03-01
• First posted: 2017-08-10
• Last updated: 2019-03-07

Locations

1 site across 1 country: Reunion