Trials / Unknown
UnknownNCT03245346
Effects of Epidural Anesthesia and Analgesia on the Prognosis in Patients Undergoing Pancreatic Cancer Surgery
Effects of Epidural Anesthesia and Analgesia on the Prognosis in Patients Undergoing Pancreatic Cancer Surgery: A Multi-center Randomized Controlled Trial
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 540 (estimated)
- Sponsor
- Fudan University · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this randomized controlled trial is to investigate the effects of epidural anesthesia and analgesia on the overall survival，disease-free survival and recovery in patients undergoing pancreatic cancer surgery. This study will also evaluate the effects of this technique on neuroendocrine, stress and inflammatory response in these patients.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | GEA | Thoracic epidural catheterization will be performed and epidural anesthesia will be maintained with 0.25% ropivacaine during surgery. General anesthesia will be maintained with inhalation (sevoflurane) and muscle relaxants will be administered when considered necessary. |
| DRUG | PCEA | Patient-controlled epidural analgesia (0.15% ropivacaine infusion) will be provided after surgery. |
| DRUG | GA | General anesthesia will be maintained with inhalation (sevoflurane) and sufentanil infusion, and muscle relaxants will be administered when considered necessary. |
| DRUG | PCIA | Patient-controlled intravenous analgesia (1ug/ml sufentanil) will be provided after surgery. |
Timeline
- Start date
- 2017-12-19
- Primary completion
- 2021-12-18
- Completion
- 2021-12-18
- First posted
- 2017-08-10
- Last updated
- 2019-12-11
Locations
3 sites across 1 country: China
Source: ClinicalTrials.gov record NCT03245346. Inclusion in this directory is not an endorsement.