NCT03240302

A Comparative Study of Sibling Oocytes: ICSI vs. the PICSI Sperm Selection Method

A Comparative Study of Sibling Oocytes, Which Examines Two Sperm Selection Methods for Top Quality of Spermatozoa , Prior Intracytoplasmic Sperm Injection (ICSI) Performance, and Their Effect on Embryo Quality and IVF Outcome: A Common Selection Method Based on Morphology (ICSI) vs. a Selection Method for Mature Spermatozoa With CD44 Receptors for Hyaluronic Acid (PICSI - Physiological Selected Intracytoplasmic Sperm Injection)

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Hillel Yaffe Medical Center · Other Government
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The aim of this research is to compare sibling oocytes using two sperm selection methods for choosing the best quality spermatozoa before they are injected into oocytes and the influence of each of these methods on embryo quality and IVF outcome.

Conditions

• Infertility

Interventions

Type	Name	Description
DEVICE	ICSI petri dish	Half of the oocytes will be placed into the standard ICSI petri dish and they will be injected with sperm with normal morphology.
DEVICE	PICSI petri dish	Half of the oocytes will be placed into a PICSI petri dish (whose bottom is coated with hyaluronic acid) and the mature spermatozoa with CD44 receptors that are attached to the bottom of the dish will be injected into them.

Timeline

• Start date: 2017-09-01
• Primary completion: 2020-09-01
• Completion: 2020-09-01
• First posted: 2017-08-07
• Last updated: 2017-08-07

Locations

1 site across 1 country: Israel