NCT03239314

Analgesic Effect of Adductor Canal Block With and Without Dexamethasone for Knee Arthroscopy

The Effect of Adding Dexamethasone to Bupivacaine in Ultrasound Guided Adductor Canal Block for Postoperative Analgesia Following Knee Arthroscopic Anterior Cruciate Ligament Reconstruction

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study was to evaluate the efficacy of ultra-sound guided adductor canal block with and without dexamethasone when added to bupivacaine on the duration of postoperative analgesia in patients undergoing arthroscopic anterior cruciate ligament reconstruction surgery using Numeric Rating Score (NRS).

Detailed description

Adductor canal block was done by Ultra-sound. After confirmation of the block and exclusion of any signs of toxicity or nerve injury, the patients operations were done under spinal anesthesia. Patients were allocated into one of 2 groups (30 patients per group). I. Group I: the patients received a single-shot of 20 ml plain bupivacaine (0.5%) +2 ml normal saline. ii.Group II: the patients received 20ml plain bupivacaine (0.5%) + 8 mg dexamethasone (2ml). Postoperative pain were assessed by Numeric Rating Scale (N.R.S) every 6 h post-operatively for 24 h. Whenever, the NRS Score was ≥4 or the patient requested pain medication, analgesia was provided by ketorolac 30 mg amp IV, then morphine 1mg ̸ kg slowly IV as a rescue analgesia. Time to first request for analgesia \& total dose of rescue analgesia were be recorded. 10\. Satisfaction score will be measured on a linear numerical scale; ranging from 0 = complete dissatisfaction to 10 = complete satisfaction. Any post-operative side effects, like nausea, vomiting, bradycardia, hypotension will be also documented. The time to first analgesic requirement will be recorded, and the cumulative, post-operative opioid consumption in 24 h post-operatively will be recorded. Assessment of Quadriceps Strength at preoperative, 6, 12, 18, and 24 h postoperative from zero to 5.

Conditions

• Postoperative Analgesia

Interventions

Type	Name	Description
DRUG	Saline Solution	Injected in the adductor canal
DRUG	Dexamethasone	Injected in the adductor canal

Timeline

• Start date: 2016-10-01
• Primary completion: 2017-06-01
• Completion: 2017-07-22
• First posted: 2017-08-04
• Last updated: 2017-08-04