NCT03238066

Salvage Brachytherapy and Interstitial Hyperthermia for Locally Recurrent Prostate Carcinoma Following Radiation Therapy

A Prospective Phase II Study of Salvage Brachytherapy in Combination With Interstitial Hyperthermia for Locally Recurrent Prostate Carcinoma Following External Beam Radiation Therapy

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 77 (estimated)
• Sponsor: University of Erlangen-Nürnberg Medical School · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Salvage brachytherapy in combination with interstitial hyperthermia for locally recurrent prostate carcinoma following external beam radiation therapy.

Detailed description

Salvage brachytherapy in combination with interstitial hyperthermia for locally recurrent prostate carcinoma following external beam radiation therapy: Salvage brachytherapy: HDRBT: 3 x 10 Gy specified on prostate capsule/tumor margin (d1, 22, 43) or PDRBT: 2 x 30 Gy specified on prostate capsule/tumor margin (d1-3, 29-31) Hyperthermia: prostate heated to 40 - 47˚C for 30-60 minutes (60 minutes recommended) prior to brachytherapy dose delivery. Maximum temperature in surrounding critical normal organs should not exceed 43˚C

Conditions

• Prostate Cancer

Interventions

Type	Name	Description
RADIATION	Brachytherapy	HDR/PDR brachytherapy
OTHER	Hyperthermia	Interstitial hyperthermia

Timeline

• Start date: 2015-04-01
• Primary completion: 2018-12-01
• Completion: 2022-04-01
• First posted: 2017-08-03
• Last updated: 2018-06-07

Locations

3 sites across 2 countries: Germany, Poland