NCT03236181

Chronic Effects of Fats on Satiety & Energy Needs

Chronic Effects of Fats on Satiety and Energy Expenditure

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 1 (actual)
• Sponsor: USDA Grand Forks Human Nutrition Research Center · Federal
• Sex: All
• Age: 20 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate the effect of dietary fat on satiety (the experience of fullness between one meal and the next) and energy metabolism over an extended period of time (chronic effects). How dietary fat sources affect satiety, appetite and energy use is unclear. The investigators will use a controlled setting for the studies. They want to know if the source of dietary fat alters satiety, satiety hormones, and energy expenditure responses after consuming different diets.

Detailed description

This work will address the interaction of obesity and dietary fatty acids in regulating satiety and energy metabolism. The primary objective is to determine the effects of chronic intake of dietary fatty acids of varied saturation and chain length on satiety, thermogenesis and energy utilization in healthy individuals. The investigators hypothesize that unsaturated fatty acids will 1) increase satiety and 2) increase energy metabolism and that 3) the fatty acid binding protein polymorphisms are associated with reduced energy expenditure in response to dietary fat intake.

Conditions

• Overweight
• Obesity

Interventions

Type	Name	Description
OTHER	SFA	High saturated fatty acid/SFA oil source
OTHER	MUFA	High monounsaturated fatty acid/MUFA oil source
OTHER	PUFA	High polyunsaturated fatty acid (linoleic)/PUFA oil source
OTHER	LCn3	High polyunsaturated fatty acid (omega-3)/LCn3 oil source

Timeline

• Start date: 2017-10-03
• Primary completion: 2018-05-24
• Completion: 2018-05-24
• First posted: 2017-08-01
• Last updated: 2018-08-03

Locations

1 site across 1 country: United States