NCT03232736

InterventiOn of Biventricular Pacemaker Function on ventrIcular Function Among Patients With LVAD's

Randomized interventiOn of Biventricular Pacemaker Function on ventrIcular Function Among Patients With mechaNical Circulatory Support Devices

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 22 (actual)
• Sponsor: University of Colorado, Denver · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The primary reason the investigators are doing this study are to understand how the right side of the heart functions in heart failure patients with left ventricular assist devices (LVADs, or "mechanical hearts"). Second, the investigators are interested in understanding how different pacemaker settings influence function of the heart at rest and activity.

Detailed description

Healthy individuals, as well as patients with advanced heart failure supported by LVADs, completed invasive hemodynamic analysis at rest and with exercise to characterize right-sided heart function at rest and with exercise during invasive cardiopulmonary exercise testing on upright cycle ergometry.

Conditions

• Heart Diseases
• Left Ventricular Dysfunction

Timeline

• Start date: 2017-10-01
• Primary completion: 2020-01-30
• Completion: 2020-01-30
• First posted: 2017-07-28
• Last updated: 2023-11-14
• Results posted: 2021-08-27

Locations

1 site across 1 country: United States