NCT03226587

Acute Effects of Whole Body Blue Light Exposure on Blood Pressure

Acute Effects of Whole Body Blue Light Exposure on Blood Pressure, Endothelial Function and Vascular Stiffness

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Heinrich-Heine University, Duesseldorf · Academic / Other
• Sex: Male
• Age: 30 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Ultraviolet light exposure was shown to be able to release nitric oxide from the skin into the blood stream and lead to an acute decrease in blood pressure and increase in vascular function. Additionally, preliminary work indicates that UV free blue light also releases nitric oxide in the skin mediating similar effects as seen with ultraviolet light A(UVA). It is the goal of the present experimental study to investigate the hemodynamic effects of whole body blue light exposure including blood pressure, endothelial function and vascular stiffness. Therefore, healthy volunteers will be exposed to 30 minutes whole body blue light (453 nm wavelength) and the change in blood pressure and endothelial function (Flow mediated dilation (FMD)), heart rate, forearm-blood flow, forearm vascular resistance central blood pressure and vascular stiffness ( pulse wave analysis by sphygmocor) will be measured. In this randomized controlled cross-over study, 20 healthy subjects aged 30 to 60 years will participate.

Conditions

• Blue Light

Interventions

Type	Name	Description
PROCEDURE	Blue light	Subjects will be exposed to blue light (453 nm wavelength) for 30 minutes
PROCEDURE	control exposure	Subjects will get control exposure to 30 minutes of whole body, which causes only comparable warming of skin as with blue light exposure.

Timeline

• Start date: 2016-08-01
• Primary completion: 2017-08-01
• Completion: 2017-08-01
• First posted: 2017-07-24
• Last updated: 2017-11-09

Locations

1 site across 1 country: Germany