NCT03224572

The Effect of Vitamin C on Quality of Life of Terminal Cancer Patients

• Status: Unknown
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: National Taiwan University Hospital · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

This study determines whether high dose vitamin C is effective for quality of life in terminal cancer patients.

Detailed description

The investigator's project is a single medical center, randomized double- blinded trial. The target group is terminal cancer patients at Palliative care clinics. The experimental group will receive intravenous high-dose vitamin C 30 g in 500 ml normal saline in 1-hour infusion, once per week, and total 4-week treatment. The control group will receive 500 ml normal saline in 1-hour infusion, once per week, and total 4-week treatment. The primary outcome is the improvement of quality of life, measured by European Organization for Research and Treatment of cancer (EORTC). The secondary outcome is the survival analysis.The participants will be followed up weekly for 2 weeks, then bi-weekly for 6 months.

Conditions

• Vitamin C Deficiency

Interventions

Type	Name	Description
DRUG	high-dose vitamin C 30gm	High-dose vitamin C 30 gm in 500 ml normal saline, once per week, and total 4-week treatment.
OTHER	normal saline	500ml normal saline, once per week, and total 4-week treatment

Timeline

• Start date: 2018-01-01
• Primary completion: 2018-12-01
• Completion: 2018-12-01
• First posted: 2017-07-21
• Last updated: 2018-01-02

Locations

1 site across 1 country: Taiwan