NCT03223389

Fat Metabolites and Gut Hormones

Effects of Fat Metabolites on Gut Hormone Secretion After Gastric Bypass Surgery

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Hvidovre University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

To investigate the effects of different fat metabolites on gut hormone secretion in gastric bypass operated subjects and BMI-matched controls.

Detailed description

Dietary triglycerides are hydrolyzed during digestion to two fatty acids and one 2-monoacyl glycerol. The study will investigate the effects of these different fat components on gut hormone secretion in gastric bypass operated patients and non-operated BMI-matched controls.

Conditions

• Overweight and Obesity
• Type 2 Diabetes
• Bariatric Surgery
• Gut Hormones
• Dietary Fat

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	C-8 dietary oil	Ingestion of 13.15 g C-8 dietary oil providing 0.0216 mol of triglycerides.
DIETARY_SUPPLEMENT	Tricaprylin	Ingestion of 10.17 g tricaprylin providing 0.0216 mol of triglycerides.
DIETARY_SUPPLEMENT	Olive oil	Ingestion of 19 g olive oil providing 0.0216 mol of triglycerides.

Timeline

• Start date: 2017-08-07
• Primary completion: 2018-12-01
• Completion: 2018-12-01
• First posted: 2017-07-21
• Last updated: 2017-07-26

Locations

1 site across 1 country: Denmark